Stem Cells and their History
What are stem cells?
Stem cells are cell develop in animal which is plastic in nature and differentiated into types of cells. All other cells with specialized function are generated under the proper microenvironment in body.One stem cell can produce one stem cell replica and one other type of cell which can be further differentiated and develop into cell line. Stem cell have ability to self- renew, differentiation, plasticity (moldability)
History of stem cells
In 19th century Theodor Boveri and Valentin Haecker coined the term stem cell. They both are zoologist.(Pic 2)Artur Pappenheim was first discover the theory of blood stem cells in 20th century. He was a German haematologist. (Pic 3). Georges Mathe was perform the bone marrow transplant using stem cell therapy in 1958.he was oncologist and immunologist.(Pic 4)
Ernest McCulloch and James Till. define the main properties of stem cells. In 1960s at university of Toronto. They also discover the blood forming stem cell and hematopoietic stem cell.(Pic 5)
In 1981 Martin Evans and Matthew Kaufman isolate the embryonic stem cell and culture it in mouse blastocysts. (Pic 6)
In 2006 Shinya Yamanaka convert the fibroblast into pluripotent stem cell by modifying the expression of genes. He win a Nobel prize. (Pic 7)
This are the about the stem cells and the history. We will study about the types of stem cells.
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Disclaimer - I do not claim any of the data here. I have referred various books and articles and represented here. All this is just to make concepts easy. Only important and precise data has been provided. It is not for commercial purpose. Your valuable suggestions are always welcome.
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