Biospace

Types of stem cells Totipotent : It is a stem cell which can produce total types or all types of other cell lineages is called totipotent or total potent cells. Eg: zygote and first 4-8 cells after cleavage.  Pluripotent: A stem cell which can produce all cells of embryo but not extraembryonic layers in mammals is called as pluripotent cell. Eg: cells forming inner cell mass (ICM) in mammalian development, blastocyst.  Multipotent: A stem cell retain in specific tissue of body and can only be differentiated in all type cell belonging to that tissue only. Eg: stem cell retain in adult Brains  Oligopotent: Oligopotent stem cell can self renew and differentiated in to the closely related cell type . Eg: Hematopoietic stem cell  Unipotent: Uni means one (itself) . unipotent stem cell has lowest differential potential than other types of stem cells. They are mostly found in adult tissue. Eg: muscle stem cell.  Sources of stem cells Embryonic Stem Cells                        They

What are stem cells? Stem cells are cell develop in animal which is plastic in nature and differentiated into types of cells. All other cells with specialized function are generated under the proper microenvironment in body. One stem cell can produce one stem cell replica and one other type of cell which can be further differentiated and develop into cell line. Stem cell have ability to self- renew, differentiation, plasticity (moldability) History of stem cells In 19th century Theodor Boveri and Valentin Haecker coined the term stem cell. They both are zoologist.(Pic 2) Artur Pappenheim was first discover the theory of blood stem cells in 20th century. He was a German haematologist. (Pic 3). Georges Mathe was perform the bone marrow transplant using stem cell therapy in 1958.he was oncologist and immunologist.(Pic 4) Ernest McCulloch and James Till. define the main properties of stem cells. In 1960s at university of Toronto. They also discover the blood forming stem cel